Mouse Plekhf2 activation kit by CRISPRa

SKU GA208954

Plekhf2 CRISPRa kit - CRISPR gene activation of mouse pleckstrin homology domain containing, family F (with FYVE domain) member 2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Plekhf2
• Locus ID: 71801
• Components:

  GA208954G1, Plekhf2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA208954G2, Plekhf2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA208954G3, Plekhf2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_175175
• UniProt ID: Q91WB4
• Synonyms: 1110070J07Rik; AA673237; ZFYVE18
• Summary: May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport (By similarity). Enhances cellular sensitivity to TNF-induced apoptosis.[UniProtKB/Swiss-Prot Function]