Mouse Pitpnc1 activation kit by CRISPRa

SKU GA208951

Pitpnc1 CRISPRa kit - CRISPR gene activation of mouse phosphatidylinositol transfer protein, cytoplasmic 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Pitpnc1
• Locus ID: 71795
• Components:

  GA208951G1, Pitpnc1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA208951G2, Pitpnc1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA208951G3, Pitpnc1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_145823, NM_001359616, NR_153311
• UniProt ID: Q8K4R4
• Synonyms: 1110020B03Rik; 5830436L09Rik; AI662802; AI851387; C330017I21Rik; Dnr411; rdgB-beta; RDGBB; RDGBB1
• Summary: Phosphatidylinositol transfer proteins mediate the monomeric transport of lipids by shielding a lipid from the aqueous environment and binding the lipid in a hydrophobic cavity. Able to transfer phosphatidylinositol in vitro. Isoform 2 specifically binds to phosphatidylinositol but not to other phospholipids and may play a role in the phosphoinositide-mediated signaling in the neural development.[UniProtKB/Swiss-Prot Function]