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Mouse Marchf8 activation kit by CRISPRa

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SKU
GA208943
March8 CRISPRa kit - CRISPR gene activation of mouse membrane-associated ring finger (C3HC4) 8
  $1,657.00
4 Weeks*

Other products for "Marchf8"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Marchf8
Locus ID 71779
Components

GA208943G1, Marchf8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA208943G2, Marchf8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA208943G3, Marchf8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001302383, NM_001302384, NM_001302385, NM_027920
UniProt ID Q9DBD2
Synonyms 1300017E09Rik; MARCH-VIII; Mir
Summary The protein encoded by this gene is a member of the membrane-associated really interesting new gene-CH family of proteins. These proteins are E3 ubiquitin-protein ligases that modulate antigen presentation by downregulating major histocompatibility complex class II surface expression through endocytosis. The transcript is primarily expressed by dendritic cells and macrophages. Overexpression of this gene in antigen presenting cells results in immune defective phenotypes, including resistance to autoimmune disease onset. Alternative splicing results in multiple transcript variants. provided by RefSeq, Oct 2014
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Documents
Resources
Other Versions
SKU Description Size Price
KN509791 March8 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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