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Mouse Osbpl3 activation kit by CRISPRa

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SKU
GA208909
Osbpl3 CRISPRa kit - CRISPR gene activation of mouse oxysterol binding protein-like 3
  $1,657.00
4 Weeks*

Other products for "Osbpl3"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Osbpl3
Locus ID 71720
Components

GA208909G1, Osbpl3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA208909G2, Osbpl3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA208909G3, Osbpl3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001163645, NM_001347213, NM_027881
UniProt ID Q9DBS9
Synonyms 1200014M06Rik; 6720421I08Rik; A530055M08; ORP-3; ORP3; OSBP3
Summary Phosphoinositide-binding protein which associates with both cell and endoplasmic reticulum (ER) membranes. Can bind to the ER membrane protein VAPA and recruit VAPA to plasma membrane sites, thus linking these intracellular compartments. The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface. With VAPA, may regulate ER morphology. Has a role in regulation of the actin cytoskeleton, cell polarity and cell adhesion. Binds to phosphoinositides with preference for PI(3,4)P2 and PI(3,4,5)P3. Also binds 25-hydroxycholesterol and cholesterol.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN512643 Osbpl3 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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