Mouse Mmrn1 activation kit by CRISPRa

SKU GA208673

Mmrn1 CRISPRa kit - CRISPR gene activation of mouse multimerin 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Mmrn1
• Locus ID: 70945
• Components:

  GA208673G1, Mmrn1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA208673G2, Mmrn1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA208673G3, Mmrn1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001163507, NM_027613
• UniProt ID: B2RPV6
• Synonyms: 4921530G03Rik; Emilin4; Mmrn
• Summary: Carrier protein for platelet (but not plasma) factor V/Va. Plays a role in the storage and stabilization of factor V in platelets. Upon release following platelet activation, may limit platelet and plasma factor Va-dependent thrombin generation. Ligand for integrin alpha-IIb/beta-3 and integrin alpha-V/beta-3 on activated platelets, and may function as an extracellular matrix or adhesive protein (By similarity).[UniProtKB/Swiss-Prot Function]