Mouse Zcchc8 activation kit by CRISPRa

SKU GA208590

Zcchc8 CRISPRa kit - CRISPR gene activation of mouse zinc finger, CCHC domain containing 8

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Zcchc8
• Locus ID: 70650
• Components:

  GA208590G1, Zcchc8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA208590G2, Zcchc8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA208590G3, Zcchc8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_027494
• UniProt ID: Q9CYA6
• Synonyms: 5730565F05Rik
• Summary: Scaffolding subunit of the trimeric nuclear exosome targeting (NEXT) complex, a complex that directs a subset of non-coding short-lived RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its cofactor MTREX, which links to RNA-binding protein adapters. May be involved in pre-mRNA splicing.[UniProtKB/Swiss-Prot Function]