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Mouse Plscr3 activation kit by CRISPRa

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SKU
GA208471
Plscr3 CRISPRa kit - CRISPR gene activation of mouse phospholipid scramblase 3
  $1,657.00
4 Weeks*

Other products for "Plscr3"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Plscr3
Locus ID 70310
Components

GA208471G1, Plscr3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA208471G2, Plscr3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA208471G3, Plscr3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001168497, NM_023564, NR_033133
UniProt ID Q9JIZ9
Synonyms 2210403O21Rik; 2610037N06Rik; ESTM3; X83310
Summary May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN513493 Plscr3 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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