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Mouse Vps36 activation kit by CRISPRa

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SKU
GA208438
Vps36 CRISPRa kit - CRISPR gene activation of mouse vacuolar protein sorting 36
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

TA357337 Vps36 Antibody - N-terminal region
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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Vps36
Locus ID 70160
Components

GA208438G1, Vps36 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA208438G2, Vps36 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA208438G3, Vps36 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_027338, NM_001368379
UniProt ID Q91XD6
Synonyms 1700010A24Rik; 2210415M20Rik; 2810408E15Rik; Eap45
Summary Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. Its ability to bind ubiquitin probably plays a role in endosomal sorting of ubiquitinated cargo proteins by ESCRT complexes. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. Binds phosphoinosides such as PtdIns(3,4,5)P3.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN519254 Vps36 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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