Mouse Spink2 activation kit by CRISPRa

SKU
GA208386
Spink2 CRISPRa kit - CRISPR gene activation of mouse serine peptidase inhibitor, Kazal type 2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Spink2
Locus ID 69982
Components

GA208386G1, Spink2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA208386G2, Spink2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA208386G3, Spink2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001289764, NM_001289767, NM_001289768, NM_183284
UniProt ID Q8BMY7
Synonyms 1700007F22Rik; AV038945; HUSI-II
Summary As a strong inhibitor of acrosin, it is required for normal spermiogenesis. It probably hinders premature activation of proacrosin and other proteases, thus preventing the cascade of events leading to spermiogenesis defects (PubMed:21705336, PubMed:28554943). May be involved in the regulation of serine protease-dependent germ cell apoptosis (PubMed:21705336). It also inhibits trypsin (PubMed:21705336).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN516616 Spink2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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