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Mouse Nkiras1 activation kit by CRISPRa

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SKU
GA208295
Nkiras1 CRISPRa kit - CRISPR gene activation of mouse NFKB inhibitor interacting Ras-like protein 1
  $1,657.00
4 Weeks*

Other products for "Nkiras1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Nkiras1
Locus ID 69721
Components

GA208295G1, Nkiras1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA208295G2, Nkiras1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA208295G3, Nkiras1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001316711, NM_001316712, NM_023526
UniProt ID Q8CEC5
Synonyms 2400004O09Rik; kappaB-Ras1; KBRAS1
Summary Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB (By similarity).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN511015 Nkiras1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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