Mouse Tlcd3b activation kit by CRISPRa

SKU GA207989

Fam57b CRISPRa kit - CRISPR gene activation of mouse family with sequence similarity 57, member B

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Tlcd3b
• Locus ID: 68952
• Components:

  GA207989G1, Tlcd3b gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA207989G2, Tlcd3b gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA207989G3, Tlcd3b gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001146347, NM_026884, NM_029978
• UniProt ID: Q7TNV1
• Synonyms: 1500016O10Rik; A330104J06Rik; AI413816; AW060769
• Summary: Involved in ceramide synthesis. In vitro, isoform 3 stimulates the production of C16-, C18- and C20-ceramides, isoform 1 slightly increases the levels of C18- and C20-ceramides, while isoform 2 exhibits only minimal activity. May interfere with adipogenesis by stimulating ceramide synthesis.[UniProtKB/Swiss-Prot Function]