Mouse Vps53 activation kit by CRISPRa

SKU
GA207770
Vps53 CRISPRa kit - CRISPR gene activation of mouse VPS53 GARP complex subunit
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Vps53
Locus ID 68299
Components

GA207770G1, Vps53 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA207770G2, Vps53 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA207770G3, Vps53 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_026664, NM_001364738
UniProt ID Q8CCB4
Synonyms 2010002A08Rik; 2310040I21Rik; 3100002B05Rik; Hccs1
Summary Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD. Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN519266 Vps53 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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