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Mouse Pak1ip1 activation kit by CRISPRa

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SKU
GA207672
Pak1ip1 CRISPRa kit - CRISPR gene activation of mouse PAK1 interacting protein 1
  $1,657.00
4 Weeks*

Other products for "Pak1ip1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Pak1ip1
Locus ID 68083
Components

GA207672G1, Pak1ip1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA207672G2, Pak1ip1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA207672G3, Pak1ip1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_026550
UniProt ID Q9DCE5
Synonyms 5830431I15Rik; 5930415H02Rik; AA419825; AI314040; AW556169; Gdpd1; PIP1
Summary Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which has been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42. May be involved in ribosomal large subunit assembly.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN512763 Pak1ip1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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