Mouse Paip2 activation kit by CRISPRa

SKU
GA207556
Paip2 CRISPRa kit - CRISPR gene activation of mouse polyadenylate-binding protein-interacting protein 2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Paip2
Locus ID 67869
Components

GA207556G1, Paip2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA207556G2, Paip2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA207556G3, Paip2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_026420, NM_001357470, NM_001357471, NM_001357472, NM_001357473
UniProt ID Q9D6V8
Synonyms 2310050K10Rik; AU045972
Summary Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization (By similarity).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN512760 Paip2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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