Mouse Gpsm1 activation kit by CRISPRa

SKU GA207537

Gpsm1 CRISPRa kit - CRISPR gene activation of mouse G-protein signalling modulator 1 (AGS3-like, C. elegans)

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Gpsm1
• Locus ID: 67839
• Components:

  GA207537G1, Gpsm1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA207537G2, Gpsm1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA207537G3, Gpsm1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001199146, NM_001199147, NM_153410, NM_001355574, NM_001355575, NM_001355576
• UniProt ID: Q6IR34
• Synonyms: 1810037C22Rik; Ags3; AW107933
• Summary: Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G-protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction.[UniProtKB/Swiss-Prot Function]