Mouse Dnajb11 activation kit by CRISPRa

SKU
GA207536
Dnajb11 CRISPRa kit - CRISPR gene activation of mouse DnaJ heat shock protein family (Hsp40) member B11
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Dnajb11
Locus ID 67838
Components

GA207536G1, Dnajb11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA207536G2, Dnajb11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA207536G3, Dnajb11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001190804, NM_001190805, NM_026400
UniProt ID Q99KV1
Synonyms 1810031F23Rik; ABBP-2; AL024055; Dj9; ERdj3; ERj3p
Summary As a co-chaperone for HSPA5 it is required for proper folding, trafficking or degradation of proteins. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity. It is necessary for maturation and correct trafficking of PKD1.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN504665 Dnajb11 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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