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Mouse Chd8 activation kit by CRISPRa

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SKU
GA207509
Chd8 CRISPRa kit - CRISPR gene activation of mouse chromodomain helicase DNA binding protein 8
  $1,657.00
4 Weeks*

Other products for "Chd8"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Chd8
Locus ID 67772
Components

GA207509G1, Chd8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA207509G2, Chd8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA207509G3, Chd8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_201637, NM_001010928
UniProt ID Q09XV5
Synonyms 5830451P18Rik; AU015341; Duplin; HELSNF1; mKIAA1564
Summary This gene encodes a member of the chromodomain-helicase-DNA binding protein family, which is characterized by a SNF2-like domain and two chromatin organization modifier domains. The encoded protein also contains brahma and kismet domains, which is common to the subfamily of chromodomain-helicase-DNA binding proteins to which this protein belongs. In mammals, this gene has been shown to function in several processes including transcriptional regulation, epigenetic remodeling, promotion of cell proliferation, and regulation of RNA synthesis. Knockout of this gene causes early embryonic lethality due to widespread apoptosis. Heterozygous loss of function mutations result in autism spectrum disorder-like behaviors that include increased anxiety, repetitive behavior, and altered social behavior. provided by RefSeq, Dec 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN503252 Chd8 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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