Mouse Aadac activation kit by CRISPRa

SKU GA207499

Aadac CRISPRa kit - CRISPR gene activation of mouse arylacetamide deacetylase

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Aadac
• Locus ID: 67758
• Components:

  GA207499G1, Aadac gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA207499G2, Aadac gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA207499G3, Aadac gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_023383
• UniProt ID: Q99PG0
• Synonyms: 5033417E09Rik; Aada; AI265437
• Summary: Displays cellular triglyceride lipase activity in liver, increases the levels of intracellular fatty acids derived from the hydrolysis of newly formed triglyceride stores and plays a role in very low-density lipoprotein assembly (By similarity). Displays serine esterase activity in liver. Deacetylates a variety of arylacetamide substrates, including xenobiotic compounds and procarcinogens, converting them to the primary arylamide compounds and increasing their toxicity.[UniProtKB/Swiss-Prot Function]