Mouse Kcnv1 activation kit by CRISPRa

SKU GA207363

Kcnv1 CRISPRa kit - CRISPR gene activation of mouse potassium channel, subfamily V, member 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Kcnv1
• Locus ID: 67498
• Components:

  GA207363G1, Kcnv1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA207363G2, Kcnv1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA207363G3, Kcnv1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_026200
• UniProt ID: Q8BZN2
• Synonyms: 2700023A03Rik; vibe
• Summary: Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes (By similarity).[UniProtKB/Swiss-Prot Function]