Mouse Socs4 activation kit by CRISPRa

SKU
GA207249
Socs4 CRISPRa kit - CRISPR gene activation of mouse suppressor of cytokine signaling 4
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Socs4
Locus ID 67296
Components

GA207249G1, Socs4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA207249G2, Socs4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA207249G3, Socs4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_080843
UniProt ID Q91ZA6
Synonyms 3110032M18Rik; A730004F22Rik; AI427843; AU015727; AU015859; Socs7
Summary SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR (By similarity).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN516457 Socs4 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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