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Mouse Fancl activation kit by CRISPRa

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SKU
GA207094
Fancl CRISPRa kit - CRISPR gene activation of mouse Fanconi anemia, complementation group L
  $1,657.00
4 Weeks*

Other products for "Fancl"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Fancl
Locus ID 67030
Components

GA207094G1, Fancl gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA207094G2, Fancl gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA207094G3, Fancl gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001277273, NM_025923, NR_102382
UniProt ID Q9CR14
Synonyms 2010322C19Rik; AW554273; B230118H11Rik; gcd; Phf9; Pog
Summary This gene encodes the complementation group L subunit of the multimeric Fanconi anemia (FA) nuclear complex composed of proteins encoded by over ten Fanconi anemia complementation (FANC) group genes. The FA complex is necessary for protection against DNA damage. This gene product, an E3 ubiquitin ligase, catalyzes and is required for the monoubiquitination of the protein encoded by the Fanconi anemia, complementation group D2 gene, a critical step in the FA pathway (PMID: 12973351, 21229326). In mouse, mutations of this E3 ubiquitin ligase gene can lead to infertility in adult males and females, and a deletion of this gene can cause embryonic lethality in some genetic backgrounds. A pseudogene of this gene has been identified on chromosome 1. Alternative splicing results in multiple transcript variants. provided by RefSeq, Mar 2013
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Documents
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Other Versions
SKU Description Size Price
KN505750 Fancl - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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