Mouse Arrdc4 activation kit by CRISPRa

SKU GA206764

Arrdc4 CRISPRa kit - CRISPR gene activation of mouse arrestin domain containing 4

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Arrdc4
• Locus ID: 66412
• Components:

  GA206764G1, Arrdc4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA206764G2, Arrdc4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA206764G3, Arrdc4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001042592, NM_025549
• UniProt ID: A0A0B4J1F4
• Synonyms: 2410003C09Rik; AV216361
• Summary: Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates (PubMed:27462458). Plays a role in endocytosis of activated G protein-coupled receptors (GPCRs) (By similarity). Through an ubiquitination-dependent mechanism plays also a role in the incorporation of SLC11A2 into extracellular vesicles (PubMed:27462458). May play a role in glucose uptake (By similarity).[UniProtKB/Swiss-Prot Function]