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Mouse Psenen activation kit by CRISPRa

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SKU
GA206717
Psenen CRISPRa kit - CRISPR gene activation of mouse presenilin enhancer gamma secretase subunit
  $1,657.00
4 Weeks*

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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Psenen
Locus ID 66340
Components

GA206717G1, Psenen gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA206717G2, Psenen gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA206717G3, Psenen gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_025498, NM_001364016, NM_001364017
UniProt ID Q9CQR7
Synonyms 1700023M09Rik; Pen-2
Summary Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein) (PubMed:12522139, PubMed:24941111). The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels (Probable). PSENEN modulates both endoproteolysis of presenilin and gamma-secretase activity (PubMed:12522139, PubMed:24941111).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN514073 Psenen - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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