Mouse Map3k20 activation kit by CRISPRa

SKU
GA206531
Map3k20 CRISPRa kit - CRISPR gene activation of mouse mitogen-activated protein kinase kinase kinase 20
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Map3k20
Locus ID 65964
Components

GA206531G1, Map3k20 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA206531G2, Map3k20 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA206531G3, Map3k20 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001164791, NM_023057, NM_178084
UniProt ID Q9ESL4
Synonyms AV006891; B230120H23Rik; MLTK; MLTKalpha; MLTKbeta; Zak
Summary Stress-activated component of a protein kinase signal transduction cascade. Regulates the JNK and p38 pathways (PubMed:11042189). Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14 (By similarity). Pro-apoptotic. Role in regulation of S and G2 cell cycle checkpoint by direct phosphorylation of CHEK2 (By similarity). Involved in limb development (PubMed:26755636).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN519580 Map3k20 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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