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Mouse Twsg1 activation kit by CRISPRa

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SKU
GA206527
Twsg1 CRISPRa kit - CRISPR gene activation of mouse twisted gastrulation BMP signaling modulator 1
  $1,657.00
4 Weeks*

Other products for "Twsg1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Twsg1
Locus ID 65960
Components

GA206527G1, Twsg1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA206527G2, Twsg1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA206527G3, Twsg1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_023053
UniProt ID Q9EP52
Synonyms 1810013J15Rik; 9030422N06Rik; AW552143; D17Ertd403e; Tsg; Twg
Summary May be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN518501 Twsg1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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