Mouse Cables1 activation kit by CRISPRa

SKU
GA206420
Cables1 CRISPRa kit - CRISPR gene activation of mouse CDK5 and Abl enzyme substrate 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Cables1
Locus ID 63955
Components

GA206420G1, Cables1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA206420G2, Cables1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA206420G3, Cables1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001146287, NM_022021
UniProt ID Q9ESJ1
Synonyms Cables; ik3-1
Summary Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death (By similarity).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN502402 Cables1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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