Mouse Ghrl activation kit by CRISPRa

SKU
GA206318
Ghrl CRISPRa kit - CRISPR gene activation of mouse ghrelin
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Ghrl
Locus ID 58991
Components

GA206318G1, Ghrl gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA206318G2, Ghrl gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA206318G3, Ghrl gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001286404, NM_001286405, NM_001286406, NM_021488, NR_138135
UniProt ID Q9EQX0
Synonyms 2210006E23Rik; Ghr; m46; MTLRP; MTLRPAP
Summary This gene encodes a preproprotein that undergoes proteolytic processing to yield two bioactive peptides, ghrelin and obestatin. The hormone ghrelin plays a role in enhancing appetite and has numerous other biological functions that include stimulating the secretion of growth hormone (somatotropin) from the anterior pituitary gland. Obestatin is thought to be a hormone that functions in decreasing appetite. Mice lacking the encoded protein develop normally and exhibit no gross anatomical abnormalities. This gene encodes distinct isoforms, some or all of which may undergo similar proteolytic processing. provided by RefSeq, Jul 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN506449 Ghrl - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

The proximal first exon architecture of the murine ghrelin gene is highly similar to its human orthologue
Seim, Carter, Herington et al
BMC Res Notes (2009) 2, 85 DOI: 10.1186/1756-0500-2-85
Cited by 4
AI Summary: OriGene’s qPCR primer sets (OriGene, MK052504 and MK052505) were used in this study to quantify murine ghrelin gene transcripts by real-time RT-PCR, enabling the identification of tissue-specific expression patterns of alternative first exons.
FigureFigureFigure
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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