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Mouse Nelfb activation kit by CRISPRa

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SKU
GA206261
Nelfb CRISPRa kit - CRISPR gene activation of mouse negative elongation factor complex member B
  $1,657.00
4 Weeks*

Other products for "Nelfb"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Nelfb
Locus ID 58202
Components

GA206261G1, Nelfb gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA206261G2, Nelfb gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA206261G3, Nelfb gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_021393
UniProt ID Q8C4Y3
Synonyms A730008L03Rik; AB041607; AI663983; Cobra1; Nelf-b
Summary This gene encodes subunit B of a metazoan-specific, four-subunit protein complex that regulates promoter-proximal pausing of RNA polymerase II. RNA polymerase II pausing is thought to be important for coordination of gene transcription during embryonic development and stress responses. Consistently, disruption of this gene in mouse causes inner cell mass deficiency and embryonic lethality. In addition, this gene is required for maintenance of mouse embryonic stem cells by preventing expression of developmental genes. In adult mice, conditional deletion of this gene results in cardiomyopathy and impaired response to cardiac stress. Multiple protein isoforms are encoded through the use of a non-AUG (CUG) initiation codon and an alternative downstream AUG initiation codon. In addition, alternative splicing results in multiple transcript variants. provided by RefSeq, Jul 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN510895 Nelfb - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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