Mouse Pidd1 activation kit by CRISPRa

SKU
GA206242
Pidd1 CRISPRa kit - CRISPR gene activation of mouse p53 induced death domain protein 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Pidd1
Locus ID 57913
Components

GA206242G1, Pidd1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA206242G2, Pidd1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA206242G3, Pidd1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_022654, NM_001360523, NM_001360524, NR_153591
UniProt ID Q9ERV7
Synonyms 1200011D09Rik; AU042446; Lrdd; Pidd
Summary Component of the DNA damage/stress response pathway that functions downstream of p53/TP53 and can either promote cell survival or apoptosis (PubMed:10973264). Associated with CRADD and the CASP2 caspase, it forms the PIDDosome a complex that activates CASP2 and triggers apoptosis. Associated with IKBKG and RIPK1, it enhances sumoylation and ubiquitination of IKBKG which is important for activation of the transcription factor NF-kappa-B (By similarity).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN509410 Lrdd - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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