Mouse C1d activation kit by CRISPRa

SKU GA206161

C1d CRISPRa kit - CRISPR gene activation of mouse C1D nuclear receptor co-repressor

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: C1d
• Locus ID: 57316
• Components:

  GA206161G1, C1d gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA206161G2, C1d gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA206161G3, C1d gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001330649, NM_020558
• UniProt ID: O35473
• Synonyms: 1110036E10Rik; AI875855; SUN-CoR
• Summary: Plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA; this function may include MPHOSPH6. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB (By similarity).[UniProtKB/Swiss-Prot Function]