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Mouse Sphk2 activation kit by CRISPRa

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SKU
GA206044
Sphk2 CRISPRa kit - CRISPR gene activation of mouse sphingosine kinase 2
  $1,657.00
4 Weeks*

Other products for "Sphk2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Sphk2
Locus ID 56632
Components

GA206044G1, Sphk2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA206044G2, Sphk2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA206044G3, Sphk2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001172561, NM_020011, NM_203280
UniProt ID Q9JIA7
Synonyms C76851
Summary This gene encodes a kinase that phosphorylates sphingosine into sphingosine-1-phosphate, which is involved in cell differentiation, motility, and apoptosis. The encoded protein plays a role in maintaining cellular levels of sphingosine-1-phosphate. The gene product also enhances apoptosis in different cell types and suppresses cellular proliferation. In mast cells, the encoded protein is necessary for influx of calcium, protein kinase C activation, and cytokine production and degranulation. Alternative splicing results in multiple transcript variants. provided by RefSeq, Feb 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN516600 Sphk2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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