Mouse Trpc4ap activation kit by CRISPRa

SKU
GA205951
Trpc4ap CRISPRa kit - CRISPR gene activation of mouse transient receptor potential cation channel, subfamily C, member 4 associated protein
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Trpc4ap
Locus ID 56407
Components

GA205951G1, Trpc4ap gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA205951G2, Trpc4ap gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA205951G3, Trpc4ap gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001163452, NM_019828
UniProt ID Q9JLV2
Synonyms 4833429F06Rik; D2Ertd113e; mFLJ00177; Trrp4ap; truss
Summary Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC (By similarity). Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN518293 Trpc4ap - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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