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Mouse Tmem59 activation kit by CRISPRa

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SKU
GA205931
Tmem59 CRISPRa kit - CRISPR gene activation of mouse transmembrane protein 59
  $1,657.00
4 Weeks*

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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Tmem59
Locus ID 56374
Components

GA205931G1, Tmem59 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA205931G2, Tmem59 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA205931G3, Tmem59 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_029565
UniProt ID Q9QY73
Synonyms 1110001M20Rik; 3110046P06Rik; AI256529; D4Ertd20e; MTDCF1; ORF18
Summary Acts as a regulator of autophagy in response to S.aureus infection by promoting activation of LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C). Acts by interacting with ATG16L1, leading to promote a functional complex between LC3 and ATG16L1 and promoting LC3 lipidation and subsequent activation of autophagy. Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. Inhibits APP transport to the cell surface and further shedding.UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN517882 Tmem59 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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