Mouse Hes6 activation kit by CRISPRa

SKU
GA205772
Hes6 CRISPRa kit - CRISPR gene activation of mouse hairy and enhancer of split 6
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Hes6
Locus ID 55927
Components

GA205772G1, Hes6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA205772G2, Hes6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA205772G3, Hes6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_019479, NM_001360899, NM_001360900
UniProt ID Q9JHE6
Synonyms AI326893; bHLHb41
Summary Does not bind DNA itself but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. Also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCF3/E47, allowing ASCL1 and TCF3 to up-regulate transcription in its presence. Promotes cell differentiation.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN507675 Hes6 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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