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Mouse Il36rn activation kit by CRISPRa

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SKU
GA205715
Il1f5 CRISPRa kit - CRISPR gene activation of mouse interleukin 1 family, member 5 (delta)
  $1,657.00
4 Weeks*

Other products for "Il36rn"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Il36rn
Locus ID 54450
Components

GA205715G1, Il36rn gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA205715G2, Il36rn gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA205715G3, Il36rn gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001146087, NM_001146088, NM_019451
UniProt ID Q9QYY1
Synonyms AI413231; Fil1delta; Il-1h3; IL-36Ra; Il1hy1; IL36RN
Summary Inhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2/IL-36R and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor. Proposed to play a role in skin inflammation. May be involved in the innate immune response to fungal pathogens. May activate an anti-inflammatory signaling pathway by recruiting SIGIRR.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN508252 Il1f5 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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