Mouse Rfx5 activation kit by CRISPRa

SKU GA205625

Rfx5 CRISPRa kit - CRISPR gene activation of mouse regulatory factor X, 5 (influences HLA class II expression)

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Rfx5
• Locus ID: 53970
• Components:

  GA205625G1, Rfx5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA205625G2, Rfx5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA205625G3, Rfx5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_017395, NM_001355705, NM_001355706, NM_001355707
• UniProt ID: Q9JL61
• Summary: Activates transcription from class II MHC promoters. Recognizes X-boxes. Mediates cooperative binding between RFX and NF-Y. RFX binds the X1 box of MHC-II promoters.[UniProtKB/Swiss-Prot Function]