Mouse Clpp activation kit by CRISPRa

SKU GA205618

Clpp CRISPRa kit - CRISPR gene activation of mouse caseinolytic mitochondrial matrix peptidase proteolytic subunit

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Clpp
• Locus ID: 53895
• Components:

  GA205618G1, Clpp gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA205618G2, Clpp gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA205618G3, Clpp gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_017393
• UniProt ID: O88696
• Synonyms: AU019820; D17Wsu160e
• Summary: Protease component of the Clp complex that cleaves peptides and various proteins in an ATP-dependent process. Has low peptidase activity in the absence of CLPX. The Clp complex can degrade CSN1S1, CSN2 and CSN3, as well as synthetic peptides (in vitro) and may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates (By similarity).[UniProtKB/Swiss-Prot Function]