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Mouse Arhgef25 activation kit by CRISPRa

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SKU
GA205502
Arhgef25 CRISPRa kit - CRISPR gene activation of mouse Rho guanine nucleotide exchange factor (GEF) 25
  $1,657.00
4 Weeks*

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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Arhgef25
Locus ID 52666
Components

GA205502G1, Arhgef25 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA205502G2, Arhgef25 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA205502G3, Arhgef25 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001166413, NM_028027, NM_001358557, NM_001358558
UniProt ID Q9CWR0
Synonyms 2410008H17Rik; D10Ertd610e; GEFT
Summary May play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. It works as a guanine nucleotide exchange factor for Rho family of small GTPases. Links specifically G alpha q/11-coupled receptors to RHOA activation (By similarity). May be an important regulator of processes involved in axon and dendrite formation. In neurons seems to be an exchange factor primarily for RAC1. Involved in skeletal myogenesis.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN501533 Arhgef25 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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