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Mouse Suz12 activation kit by CRISPRa

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SKU
GA205495
Suz12 CRISPRa kit - CRISPR gene activation of mouse SUZ12 polycomb repressive complex 2 subunit
  $1,657.00
4 Weeks*

Other products for "Suz12"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Suz12
Locus ID 52615
Components

GA205495G1, Suz12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA205495G2, Suz12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA205495G3, Suz12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001163018, NM_199196
UniProt ID Q80U70
Synonyms 2610028O16Rik; AI195385; AU016842; AW536442; D11Ertd530e; mKIAA0160
Summary This gene encodes a core component of the polycomb repressive complex 2 (PRC2) that also includes, at least, embryonic ectoderm development protein (EED) and enhancer of zeste homolog 1 or 2 (EZH1 or EZH2). Through the methyltransferase activity of EZH1 or EZH2, the PRC2 complex methylates Lys9 and Lys27 of histone 3 and Lys26 of histone 1, leading to recruitment of the PRC1 complex, histone 2A ubiquitylation and transcriptional repression of the target genes. This gene product is essential for the activity and integrity of the PRC2 complex, and is required for X chromosome inactivation, stem cell maintenance and differentiation. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2009
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Documents
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Other Versions
SKU Description Size Price
KN517009 Suz12 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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