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Mouse Dkk3 activation kit by CRISPRa

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SKU
GA205361
Dkk3 CRISPRa kit - CRISPR gene activation of mouse dickkopf WNT signaling pathway inhibitor 3
  $1,657.00
4 Weeks*

Other products for "Dkk3"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Dkk3
Locus ID 50781
Components

GA205361G1, Dkk3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA205361G2, Dkk3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA205361G3, Dkk3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_015814, NM_001360257, NM_001360260, NM_001360261
UniProt ID Q9QUN9
Synonyms AW061014; C87148
Summary Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN504601 Dkk3 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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