Mouse Lmcd1 activation kit by CRISPRa

SKU
GA205292
Lmcd1 CRISPRa kit - CRISPR gene activation of mouse LIM and cysteine-rich domains 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Lmcd1
Locus ID 30937
Components

GA205292G1, Lmcd1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA205292G2, Lmcd1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA205292G3, Lmcd1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_144799
UniProt ID Q8VEE1
Synonyms AW455500; AW553074; dyxin
Summary Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue-specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter. Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN509338 Lmcd1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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