Mouse Shroom3 activation kit by CRISPRa

SKU GA205172

Shroom3 CRISPRa kit - CRISPR gene activation of mouse shroom family member 3

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Shroom3
• Locus ID: 27428
• Components:

  GA205172G1, Shroom3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA205172G2, Shroom3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA205172G3, Shroom3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001077595, NM_001077596, NM_015756
• UniProt ID: Q9QXN0
• Synonyms: AL022960; D5Ertd287e; Shrm; Shrm3
• Summary: Controls cell shape changes in the neuroepithelium during neural tube closure. Induces apical constriction in epithelial cells by promoting the apical accumulation of F-actin and myosin II, and probably by bundling stress fibers. Induces apicobasal cell elongation by redistributing gamma-tubulin and directing the assembly of robust apicobasal microtubule arrays.[UniProtKB/Swiss-Prot Function]