Mouse Mmel1 activation kit by CRISPRa

SKU GA205146

Mmel1 CRISPRa kit - CRISPR gene activation of mouse membrane metallo-endopeptidase-like 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Mmel1
• Locus ID: 27390
• Components:

  GA205146G1, Mmel1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA205146G2, Mmel1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA205146G3, Mmel1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_013783
• UniProt ID: Q9JLI3
• Synonyms: Mell1; NEP2; NEPII; Nl1; SEP
• Summary: Metalloprotease involved in sperm function, possibly by modulating the processes of fertilization and early embryonic development. Degrades a broad variety of small peptides with a preference for peptides shorter than 3 kDa containing neutral bulky aliphatic or aromatic amino acid residues. Shares the same substrate specificity with MME and cleaves peptides at the same amide bond.[UniProtKB/Swiss-Prot Function]