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Mouse Ppp2r5c activation kit by CRISPRa

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SKU
GA205045
Ppp2r5c CRISPRa kit - CRISPR gene activation of mouse protein phosphatase 2, regulatory subunit B', gamma
  $1,657.00
4 Weeks*

Other products for "Ppp2r5c"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Ppp2r5c
Locus ID 26931
Components

GA205045G1, Ppp2r5c gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA205045G2, Ppp2r5c gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA205045G3, Ppp2r5c gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001081457, NM_001081458, NM_001135001, NM_012023, NM_001364204, NM_001364205, NM_001364206, NM_001364207, NM_001364208, NM_001364209, NM_001364210, NM_001364211, NM_001364212, NM_001364213, NM_001364214
UniProt ID Q60996
Synonyms 2610043M05Rik; 2700063L20Rik; AI060890; AW545884; C85228; D12Bwg0916e; mKIAA0044
Summary The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. The PP2A-PPP2R5C holoenzyme may activate TP53 and play a role in DNA damage-induced inhibition of cell proliferation. PP2A-PPP2R5C may also regulate the ERK signaling pathway through ERK dephosphorylation (By similarity).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN513779 Ppp2r5c - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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