Mouse Mapk10 activation kit by CRISPRa

SKU
GA204958
Mapk10 CRISPRa kit - CRISPR gene activation of mouse mitogen-activated protein kinase 10
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Mapk10
Locus ID 26414
Components

GA204958G1, Mapk10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA204958G2, Mapk10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA204958G3, Mapk10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001081567, NM_009158
Synonyms C230008H04Rik; JNK3; JNK3B1; JNK3B2; p54bSAPK; p493F12; SAPK(beta); Serk2
Summary The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals, and thus are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. provided by RefSeq, Dec 2017
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Other Versions
SKU Description Size Price
KN509756 Mapk10 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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