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Mouse Sigirr activation kit by CRISPRa

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SKU
GA204878
Sigirr CRISPRa kit - CRISPR gene activation of mouse single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
  $1,657.00
4 Weeks*

Other products for "Sigirr"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Sigirr
Locus ID 24058
Components

GA204878G1, Sigirr gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA204878G2, Sigirr gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA204878G3, Sigirr gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_023059, NM_001355055
UniProt ID Q9JLZ8
Synonyms AI256711; TIR8
Summary Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP (By similarity).UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN515776 Sigirr - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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