Mouse Impdh2 activation kit by CRISPRa

SKU GA204810

Impdh2 CRISPRa kit - CRISPR gene activation of mouse inosine monophosphate dehydrogenase 2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Impdh2
• Locus ID: 23918
• Components:

  GA204810G1, Impdh2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA204810G2, Impdh2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA204810G3, Impdh2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_011830
• UniProt ID: P24547
• Synonyms: IMPD
• Summary: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.[UniProtKB/Swiss-Prot Function]