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Mouse Ikzf4 activation kit by CRISPRa

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SKU
GA204745
Ikzf4 CRISPRa kit - CRISPR gene activation of mouse IKAROS family zinc finger 4
  $1,657.00
4 Weeks*

Other products for "Ikzf4"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Ikzf4
Locus ID 22781
Components

GA204745G1, Ikzf4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA204745G2, Ikzf4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA204745G3, Ikzf4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_011772, NM_001358536, NM_001358537
UniProt ID Q8C208
Synonyms A630026H08Rik; Eos; Zfpn1a4; Znfn1a4
Summary DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros-binding sequence. Interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2. May be involved in the development of central and peripheral nervous systems. Essential for the inhibitory function of regulatory T-cells (Treg). Mediates FOXP3-mediated gene silencing in regulatory T-cells (Treg) via recruitment of corepressor CTBP1 (PubMed:19696312).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN508216 Ikzf4 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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