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Mouse Zap70 activation kit by CRISPRa

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SKU
GA204677
Zap70 CRISPRa kit - CRISPR gene activation of mouse zeta-chain (TCR) associated protein kinase
  $1,657.00
4 Weeks*

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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Zap70
Locus ID 22637
Components

GA204677G1, Zap70 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA204677G2, Zap70 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA204677G3, Zap70 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001289612, NM_001289765, NM_001289766, NM_009539
UniProt ID P43404
Synonyms mrtle; mur; Srk; ZAP-70
Summary This gene encodes a member of the protein tyrosine kinase family. The encoded protein is essential for development of T lymphocytes and thymocytes, and functions in the initial step of T lymphocyte receptor-mediated signal transduction. A mutation in this gene causes chronic autoimmune arthritis, similar to rheumatoid arthritis in humans. Mice lacking this gene are deficient in alpha-beta T lymphocytes in the thymus. In humans, mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T lymphocytes. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jan 2014
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Documents
Resources
Other Versions
SKU Description Size Price
KN519581 Zap70 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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