Mouse Ube2e3 activation kit by CRISPRa

SKU GA204516

Ube2e3 CRISPRa kit - CRISPR gene activation of mouse ubiquitin-conjugating enzyme E2E 3

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Ube2e3
• Locus ID: 22193
• Components:

  GA204516G1, Ube2e3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA204516G2, Ube2e3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA204516G3, Ube2e3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_009454, NM_001356395, NR_151457, NR_151458
• UniProt ID: P52483
• Synonyms: Ubce4; ubcM2
• Summary: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination (By similarity). Participates in the regulation of transepithelial sodium transport in renal cells. May be involved in cell growth arrest.[UniProtKB/Swiss-Prot Function]